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How Do U Catch Mewtwo In Soul Silver?

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First of all, weaken it to around the YellowHP range. Then, use anything that makes it paralyzed or sleep. Then use a Dusk Ball (can be bought at Fuchsia City Pokemart) over and over until you catch it. Chances are, when its HP is yellow-ish or red, it will keep using Safeguard (which makes it immune to status problems), so parlyz it or sleep it first. Then you should be able to catch!
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Okay I'm going to try to help you out as much as I can. First you want to have a ho-oh and lugia both about in the 70 level range, you want to weaken him with a couple hits from sacred fire, and then try to hit him with a pokemon that has strength to weaken him.this is my party
Ho-Oh 73
Lugia 57
Entei 70
Suicune 67
Rhyperior 80
and a Venasaur 72. I hope that this has given you a basic idea of what to use for some what

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