Does the architecture of a building have much effect upon the people living there?

An architect friend once told me it would be possible to construct a house so mentally disruptive, that the space itself could cause a married couple to get divorced. What is your experience? How much does the structure of the place we live (or work) affect our mental and emotional state?

First off, I'd like to say that I enjoyed this question. It made me think about architecture in a different way. I'd say, yes it's very possible. Architecture is a form of art to me, that definitely can and does illicit emotions from me. That being said, if I had to live here or even work here, I'd not only be divorced but unhappy. My surroundings must be neutral or aesthetically pleasing, this example is anything but. As a matter of fact when ever I have to drive by this thing, I feel annoyed.

Now let's move on to internal living space, let's say the home was frustrating to live in. Couldn't do every day things without frustration, the money lost in building such a frustrating home. Now, I've been married for a long time. I wouldn't want to think that something like that could cause me to leave my husband and divorce. It seems so shallow. But these things I believe could erode my good nature over time. Sort of like water torture. What is that saying, "Happy wife, happy life."

Absolutely. There are even studies that show how a room or building is lit or what color it is affects us mentally and emotionally. 

Let me give three examples:

-The house from the Addams Family

-Any apartment in a ghetto,  anywhere

-Trump Tower

How could residing in any of these places NOT affect a person?

It sure would if it was like the house from 13 Ghosts !

I personally would not enter a building, house, apt or any structure that I consider ugly, scary, mass murder has happen, seances, people homes I know that say they are witches, devil, Satan or hideous... I will only knowingly enter beautiful and happy structures.

The focal point of your question seems to be "architecture" and "living" rather than, say working. So my answer would only apply to homes and not necessarily to their state of repair, location, or social environment.

Unless a design was outrageous I think most people could adapt to most houses without too much ill effect. It beats hell out of sleeping in the street. The worst I could think of is a house designed without windows which, to me, would feel like a cell. Well, more like a padded cell.

If an evil architect was intent on driving somebody mad I'm sure that designing a home where the angles were slightly off and the room measurements a little askew would be a good way to start.

Yes of course, Freemasons share the same knowledge as the pythagorians "sacred geometry,"  the "secret teachings" of all ages, also the Gnostics and Ophites which were all serpent cults of "knowledge." Anywhere "op" is mentioned this comes from the root word for serpent. There are plenty of videos online explaining sacred geometry, the seed of life, fruit of life, flower of life, the tree of life, the vesica pisces or Jesus fish, and Metratrons cube. Freemasons were not accurate about building structure for no reason, they believed it could harness and manipulate energy etc. Their lodges are set out like Solomons temple, a copy of the human body or as jesus calls it temple. This is where their rituals are played out. Another interesting video is Secrets Hidden in plain site it's long but I enjoyed it.

https://m.youtube.com/watch?v=L777RhL_Fz4