First off, I'd like to say that I enjoyed this question. It made me think about architecture in a different way. I'd say, yes it's very possible. Architecture is a form of art to me, that definitely can and does illicit emotions from me. That being said, if I had to live here or even work here, I'd not only be divorced but unhappy. My surroundings must be neutral or aesthetically pleasing, this example is anything but. As a matter of fact when ever I have to drive by this thing, I feel annoyed.
Now let's move on to internal living space, let's say the home was frustrating to live in. Couldn't do every day things without frustration, the money lost in building such a frustrating home. Now, I've been married for a long time. I wouldn't want to think that something like that could cause me to leave my husband and divorce. It seems so shallow. But these things I believe could erode my good nature over time. Sort of like water torture. What is that saying, "Happy wife, happy life."