Is there any type of Electromagnetic defense device, theoretical, experimental, or otherwise, that can disrupt a vehicle or other devices that are within a certain area? Like the size of a city block for example.

During WWII Tesla offered the US gov a weapon which would stop any aircraft from flying over the borders, by burning out their electronics. The US  gov turned him down, but when he died (prior to the end of the war) his notebook containing this idea was lost. This is why everything about Tesla was censored till the 1990's.