Maybe. But it is officially said that she has a crush with knuckles. By watching sonic x, she always flirts with him and always get in a fight with him. Theres was also one episode after sonic adventures 2 she was talking to knuckles and she said something that made his face go red and then he quickly snapped at her. She probably likes shadow because when they first met she was interested and same as shadow - because he looked at her and he looks away trying to act cool when rouge noticed him. She was also worried about him and wondered where he was (final episode) - Egg man says he couldn't believe that she is worried about shadow but she denies. She also show strong feelings for shadow in sonic the hedgehog 06 - feeling pity and concerns.
